You actually mean the end of the earth
The space is vast, and it cannot be destroyed. Because there is not such a huge power or a huge mass to actualy destroy this limitless universe.
I do not believe that "god will blow shit up" or "a commet will strike on 2012" because for both criteria there is no evidence for that.
I do believe the end of the earth will be in possibly 5000 years, 1.000.000 years later, or maybe even tomorow. We don't have a clue.