Title has the right idea.

I vote for the N64. My index fingers always get tired after a while of hitting a shoulder button like on the Playstation or Xbox controllers repeatedly. Also, a lot of the older stuff I used to play like the good ol' Genesis and Super Nintendo were tricky to use. For 3-button moves on the Genesis, it was common to put the side of the controller into the right palm and hit the buttons with 3 fingers. Not fun after a round of Pit Fighter.

The N64 controller got it right by putting the primary shoulder button at a more relaxed position and providing a solid, easy to grab grip for the right hand.

Any thoughts?