No, they're just bad.
If kayle would actually know when to use her ult you couldnt kill any carry.
Mouse Acceleration is the most retarded thing anyone can have in a pc game. It is alot easier to play without it on because you have a consistent mouse cursor speed rather than the shifting speeds from mouse acceleration. Cursor Acceleration is designed for console or gamepads where you don't have the same accuracy, control and speed of a mouse.
Lissandra feels crazy strong but I'm still pretty bad with her. Or mid in general. It's difficult to tell. New trundle is completely fucking absurd, he's SO hard to kill. I'm expecting a nerf and/or plenty of abuse of how ridiculous he is in professional games.