@Gotkicks2: First of all, original poster's title is bullshit. By which he/she means that his/her particular definition of "intelligent" people are the kind of people who would draw the same conclusions from viewing that particular picture. So basically if you don't "understand" the picture the same way that he/she does you're not intelligent. And since he/she capitalized every single word in that sentence, I fear that's not the tragedy OP believes it to be. This kind of behavior is all over the net though, so nothing surprising. "Only <insert people who have something in common here > will understand" and all that. If you belong to that particular group of people, congratulations, you "get it" and should probably pat yourself on the back. If not, well, "u are teh stoopid lulz". Aaaaaaanyway.
I take it the picture is trying to illustrate that the smarter you are, the more difficult it is to be happy. Of course it can also mean that people who wear dull-colored clothing have brains while those who wear orange do not. Anyway, I'm taking the former point of view into account here.
I'd agree, in a way. But I'd switch knowledge with awareness. I once saw a picture which illustrated things in a visually meaningful way, but I couldn't find it. Therefore, I made my own crappy MS Paint version of it, and it's located in the spoiler below.
Being more aware means that you take more things into consideration. You could draw parallels with the senses if you'd like. A person who can see, hear, talk, smell and have a sense of touch will arguably be able to experience more than one who does not.
As illustrated by the chart, the more you know, the more you realize there are things that you don't know and could possibly never know. It is very easy to attain a nihilistic point of view if you constantly look at things on a universal scale. You being just one of many billions of currently alive humans on a planet on which 99.9% of the species that ever lived are now extinct. You being on just one planet revolving around just one sun in just one galaxy, whereas hundreds of billions of galaxies exist(one billion being 1,000,000,000). You being so insignificant on the cosmic scale that it isn't even funny. However, it's not necessary to reach that conclusion. A lot of people rely on religion in order to feel as if their life has at least some meaning. A lot of people are fully content with the worldview that everything is ultimately meaningless. I agree with nihilism for the most part, but that doesn't mean I can't enjoy my life. The decision whether or not something matters is entirely mine to make. I recently saw a quote that resonated very well with me, I'll share it here. It deals with the subject very well.
"The very meaninglessness of life forces man to create his own meaning. Children, of course, begin life with an untarnished sense of wonder, a capacity to experience total joy at something as simple as the greenness of a leaf; but as they grow older, the awareness of death and decay begins to impinge on their consciousness and subtly erode their joie de vivre, their idealism — and their assumption of immortality. As a child matures, he sees death and pain everywhere about him, and begins to lose faith in the ultimate goodness of man. But, if he’s reasonably strong — and lucky — he can emerge from this twilight of the soul into a rebirth of life’s elan. Both because of and in spite of his awareness of the meaninglessness of life, he can forge a fresh sense of purpose and affirmation. He may not recapture the same pure sense of wonder he was born with, but he can shape something far more enduring and sustaining. The most terrifying fact about the universe is not that it is hostile but that it is indifferent; but if we can come to terms with this indifference and accept the challenges of life within the boundaries of death — however mutable man may be able to make them — our existence as a species can have genuine meaning and fulfillment. However vast the darkness, we must supply our own light."
Stanley Kubrick(July 26, 1928–March 7, 1999)
TL ; DR: Intelligence brings awareness, awareness can result in a very bleak outlook of the past/present/future unless you yourself(or something you believe in) give meaning to your life.