Going to Minefield is risky, but it can earn you a Sniper Rifle, and, if you don't screw up, a metric f*ckton of Frag Mines. And, after getting the snipers key, you can enter all the houses in the area, giving you access to moar shizzle.
Also, beware the burning cars.
Oh yes, and the part where Moira Brown wants you to get irradiated? It's totally worth it to get the 600 rads. Earns you a sweet perk. Though i'm not revealing which one, you'll have to find out yourself. :3