I placed my vote on madness/insanity, mostly because people do a lot of shit when they're out of their minds...
I'll use an example from my hometown, there was a guy who escaped from a asylum, came back "home" (My town), he then went to his doctor to get his medication. But she didn't want him to abuse them, so she denied him his drugz.
He raged, shattered her spine, she's now immobile.
After some time he lit her car on fire, later was her office but they managed to stop him and get him back to the asylum.
In short: If you're insane, it could cause collateral damage.