Most important to fix with the symmetry are the eyes (the lines of the iris are too obvious, try just erasing one and doing it completely separate) and change the corners of the mouth some. Maybe some more expression.. So far the mouth is only open. Make it really scream.
Eyebrows would also be nice and useful for expression. Maybe add some small horrified tears as well as a tongue that is visible. More shine in the eyes, and also, since it looks kind of worse for wear, add some dirt or scratches to the face. Bloodshot eyes are fun if you shrink the iris and add a cornea. If you want to go for a dismal and depressing atmosphere, some yellowing of the teeth and unevenness should give you what you're looking for, and when you get to the details, some stubble. By the way, the mouth from the first WIP is better than the smaller mouth in the second two.