I've yet to leave the United States just yet (tryin to go to Tokyo and Osaka Japan next year fingers crossed). However, city I have been to that I love the most is Clearwater, FL. Florida is a rather popular destination for those who live in Ohio like myself. Clearwater is somewhat like a party type of town and is a lot more "island" like if you know what I mean. I just enjoy being a tourist there lmao. My wife and I have been there, like, 4 times now? Great place. As an honorable mention, I recently went to Pittsburg PA for Tekko-con and that city is stunning.
We will some day go to California because my wife was born there and she also wants to go back. I've heard its beautiful out there as long as you know where to go. I want to go to Joshua Tree Sky Park really bad lol.